Richard Knox http://ktep.org en Vaccine Against HPV Has Cut Infections in Teenage Girls http://ktep.org/post/vaccine-against-hpv-has-cut-infections-teenage-girls A vaccine against human papillomavirus — the most common sexually transmitted infection and the cause of almost all cervical cancer — is dramatically reducing the prevalence of HPV in teenage girls.<p>The first vaccine against HPV, Merck's <a href="http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094042.htm">Gardasil</a>, was approved by the Food and Drug Administration in 2006. Wed, 19 Jun 2013 19:46:00 +0000 Richard Knox 19274 at http://ktep.org Vaccine Against HPV Has Cut Infections in Teenage Girls Triple Threat: Middle East Respiratory Virus And 2 Bird Flus http://ktep.org/post/triple-threat-middle-east-respiratory-virus-and-2-bird-flus The World Health Organization is <a href="http://www.emro.who.int/press-releases/2013/corona-virus-who-saudi-arabia-mission.html">warning</a> health care workers everywhere to suspect a disease called Middle Eastern Respiratory Syndrome, or MERS, whenever they see a case of unexplained pneumonia.<p>Monday's warning comes at the end of a six-day WHO investigation in Saudi Arabia, where 40 of the 55 cases of the respiratory disease have occurred. Mon, 10 Jun 2013 20:31:00 +0000 Richard Knox 18656 at http://ktep.org Triple Threat: Middle East Respiratory Virus And 2 Bird Flus Obama Administration Seeks To Loosen Antibiotic Approvals http://ktep.org/post/obama-administration-seeks-loosen-antibiotic-approvals Every day in hospitals all over America, thousands of patients die of infections that <em>used</em> to be curable. But the antibiotics used to treat them <a href="http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6209a3.htm?s_cid=mm6209a3_w">aren't working</a> anymore.<p>It's called <a href="http://www.niaid.nih.gov/topics/antimicrobialresistance/Pages/default.aspx">drug resistance</a>, and it's largely a consequence of antibiotics overuse. Tue, 04 Jun 2013 06:19:00 +0000 Richard Knox 18180 at http://ktep.org Obama Administration Seeks To Loosen Antibiotic Approvals A Boston Family's Struggle With TB Reveals A Stubborn Foe http://ktep.org/post/boston-familys-struggle-tb-reveals-stubborn-foe Thanks to gold-standard tuberculosis treatment and prevention programs, cases of TB in the United States have declined every year for the past two decades — to the <a href="http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6211a2.htm">lowest level</a> ever.<p>But TB's course through the Williams family in Boston shows that no nation can afford to relax its efforts to find, treat and prevent TB. Mon, 03 Jun 2013 07:34:00 +0000 Richard Knox 18114 at http://ktep.org A Boston Family's Struggle With TB Reveals A Stubborn Foe Young Women With Breast Cancer Opting For Mastectomy http://ktep.org/post/young-women-breast-cancer-opting-mastectomy Most women diagnosed with breast cancer when they're 40 or younger are choosing <a href="http://www.nlm.nih.gov/medlineplus/mastectomy.html">mastectomy</a> rather than more limited and breast-conserving <a href="http://www.breastcancer.org/treatment/surgery/lumpectomy">lumpectomy plus radiation</a>, a study of women in Massachusetts finds.<p>Moreover, most of those choosing mastectomy elect to have the other, noncancerous breast removed, too.<p>These <a href="http://abstracts2.asco.org/AbstView_132_114717.html">findings will be presented Monday</a> at the American Society Clinical Oncology's a Fri, 31 May 2013 18:15:00 +0000 Richard Knox 18015 at http://ktep.org Young Women With Breast Cancer Opting For Mastectomy Middle East Virus Spreads Between Hospitalized Patients http://ktep.org/post/middle-east-virus-spreads-between-hospitalized-patients It's been eight months since a Saudi Arabian doctor <a href="http://www.promedmail.org/direct.php?id=20120920.1302733">described</a> a previously unknown virus related to SARS. Mon, 13 May 2013 18:06:00 +0000 Richard Knox 16730 at http://ktep.org Middle East Virus Spreads Between Hospitalized Patients Officials Prepare For Another Flu Pandemic — Just In Case http://ktep.org/post/officials-prepare-another-flu-pandemic-just-case There's been a buzz of activity at the Centers for Disease Control and Prevention in Atlanta since scientists <a href="http://www.npr.org/blogs/health/2013/04/14/177087374/scientists-race-to-stay-ahead-of-new-bird-flu-virus">got their first samples</a> of a new bird flu virus from China four weeks ago.<p>Already they've prepared "seed strains" of the virus, called <a href="http://www.who.int/influenza/human_animal_interface/faq_H7N9/en/">H7N9</a>, and distributed them to vaccine manufacturers so the companies can grow them up and make them into experimental flu vaccine.<p>They've also come up Wed, 08 May 2013 06:49:00 +0000 Richard Knox 16367 at http://ktep.org Officials Prepare For Another Flu Pandemic — Just In Case Recovery Begins For Mother, Daughter Injured In Boston http://ktep.org/post/recovery-begins-mother-daughter-injured-boston The number of Boston bombing victims still in the hospital dropped to 19 as of Wednesday evening. Thu, 02 May 2013 07:03:00 +0000 Richard Knox 15956 at http://ktep.org Recovery Begins For Mother, Daughter Injured In Boston Mother And Daughter Injured In Boston Bombing Face New Future http://ktep.org/post/mother-and-daughter-injured-boston-bombing-face-new-future Forty-seven-year-old Celeste Corcoran is propped up in her hospital bed. In a nearby window is a forest of blooming white orchids from well-wishers. On the opposite wall, a big banner proclaims "Corcoran Strong."<p>She's recalling how thrilled she was to be near the finish line of the Boston Marathon, waiting for her sister Carmen Accabo to run by. "I just remember standing there, wanting to be as close as I could to catch her," Corcoran says. "I really just needed to see her face."<p>And then the first of the two bombs went off, throwing Celeste Corcoran off her feet. Wed, 01 May 2013 07:17:00 +0000 Richard Knox 15881 at http://ktep.org Mother And Daughter Injured In Boston Bombing Face New Future With Bird Flu, "Right Now, Anything Is Possible" http://ktep.org/post/bird-flu-right-now-anything-possible An international dream team of flu experts assembled in China today.<p>Underscoring the urgency that public health agencies feel about the emergence of a new kind of bird flu, the team is headed by Dr. <a href="http://www.who.int/dg/adg/fukuda/en/">Keiji Fukuda</a>, the World Health Organization's top influenza scientist.<p>Before he left Geneva, Fukuda explained the wide-open nature of the investigation in an interview with NPR.<p>"The biggest question is just what's going to happen," he told Shots. "We've had a lot of experience in the last decade with new animal influenza viruses. But ... Fri, 19 Apr 2013 09:42:00 +0000 Richard Knox 15111 at http://ktep.org With Bird Flu, "Right Now, Anything Is Possible" Boston Doctors Compare Marathon Bomb Injuries To War Wounds http://ktep.org/post/boston-doctors-compare-marathon-bomb-injuries-war-wounds Boston hospitals always staff up their emergency rooms on Marathon Day to care for runners with cramps, dehydration and the occasional heart attack.<p>But Monday, those hospitals suddenly found themselves with more than 100 traumatized patients — many of them with the kinds of injuries seen more often on a battlefield than a marathon.<p>Like most big-city hospitals these days, Tufts Medical Center runs regular disaster drills, featuring simulated patients smeared with fake blood.<p>So when word came Monday afternoon that there had been <a href="http://www.npr.org/blogs/thetwo-way/2013/04/16/17 Tue, 16 Apr 2013 12:23:00 +0000 Richard Knox 14912 at http://ktep.org Boston Doctors Compare Marathon Bomb Injuries To War Wounds Scientists Race To Stay Ahead Of New Bird Flu Virus http://ktep.org/post/scientists-race-stay-ahead-new-bird-flu-virus A precious package arrived at the Centers for Disease Control and Prevention last Thursday afternoon.<p>Inside, packed in dry ice to keep it frozen, was a vial containing millions of viruses derived from a 35-year-old Chinese housewife who <a href="http://www.nejm.org/doi/full/10.1056/NEJMoa1304459?query=featured_home">died last Tuesday</a> of respiratory and kidney failure.<p>The package was addressed to the CDC's top flu virologist, <a href="http://www.cdc.gov/ncird/div/flu/flu-bios.html">Nancy Cox</a>. Sun, 14 Apr 2013 08:57:00 +0000 Richard Knox 14779 at http://ktep.org Scientists Race To Stay Ahead Of New Bird Flu Virus Human Cases Of Bird Flu In China Draw Scrutiny http://ktep.org/post/human-cases-bird-flu-china-draw-scrutiny Sixteen cases of a new flu around Shanghai have touched off a major effort to determine what kind of threat this new bug might be.<p>The victims range in age from 4 to 87 years old. Six have died. It is a tragedy for them and their families, but is it a global crisis?<p>To understand why so few cases are generating so much concern, the first thing to know is that no flu virus like this one — called H7N9 — has ever been known to infect humans before.<p>That immediately grabs the attention of flu pros. Fri, 05 Apr 2013 22:04:00 +0000 Richard Knox 14251 at http://ktep.org Human Cases Of Bird Flu In China Draw Scrutiny Novartis Ruling Reverberates Past India's Borders http://ktep.org/post/novartis-ruling-reverberates-past-indias-borders India's Supreme Court says drug maker Novartis can't hold onto its patent for the pricey cancer drug Gleevec simply by tweaking its chemical formula. That means generic drug makers can keep making a form of the drug at a tenth of Novartis's price — for the Indian market and for other low- and middle-income markets. Consumer advocates call it a major advance for access to generic drugs. Novartis and drug industry allies say it will chill companies' willingness to produce innovative products. Tue, 02 Apr 2013 09:28:00 +0000 Richard Knox 13919 at http://ktep.org As Stroke Risk Rises Among Younger Adults, So Does Early Death http://ktep.org/post/stroke-risk-rises-among-younger-adults-so-does-early-death Most people (including a lot of doctors) think of a stroke as something that happens to old people. But the rate is <a href="http://jama.jamanetwork.com/article.aspx?articleid=1669801">increasing</a> among those in their 50s, 40s and even younger.<p>In one recent 10-year period, the rate of strokes in Americans younger than 55 went up 84 percent among whites and 54 percent among blacks. Mon, 01 Apr 2013 07:21:00 +0000 Richard Knox 13840 at http://ktep.org As Stroke Risk Rises Among Younger Adults, So Does Early Death Sorting Out The Mammogram Debate: Who Should Get Screened When? http://ktep.org/post/sorting-out-mammogram-debate-who-should-get-screened-when Mammography outcomes from nearly a million U.S. Tue, 19 Mar 2013 16:39:00 +0000 Richard Knox 13050 at http://ktep.org Sorting Out The Mammogram Debate: Who Should Get Screened When? To Control Asthma, Start With The Home Instead Of The Child http://ktep.org/post/control-asthma-start-home-instead-child Nothing sends more kids to the hospital than <a href="http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001196/">asthma</a>.<p>So when doctors at <a href="http://www.childrenshospital.org/">Children's Hospital</a> in Boston noticed they kept seeing an unusually high number of asthmatic kids from certain low-income neighborhoods, they wondered if they could do something about the environment these kids were living in.<p>It's well-known that <a href="http://www.mayoclinic.com/health/asthma-attack/DS01068">asthma attacks</a> are <a href="http://www.cdc.gov/asthma/triggers.html">triggered</a> by dust, Mon, 18 Mar 2013 07:22:00 +0000 Richard Knox 12925 at http://ktep.org To Control Asthma, Start With The Home Instead Of The Child More Patients Keep HIV At Bay Without Antiviral Drugs http://ktep.org/post/more-patients-keep-hiv-bay-without-antiviral-drugs Just last week AIDS researchers were excited about a <a href="http://www.npr.org/blogs/health/2013/03/04/173258954/scientists-report-first-cure-of-hiv-in-a-child-say-its-a-game-changer">Mississippi toddler</a> whose blood has remained free of HIV many months after she stopped getting antiviral drugs – what doctors call a "<a href="http://www.iasociety.org/Default.aspx?pageId=583">functional cure</a>."<p>Now French researchers <a href="http://www.anrs.fr/Rubriques-transversales/Presse">confirm</a> they've found 14 adults whose immune systems are apparently controlling HIV without medication.<p> Fri, 15 Mar 2013 16:57:00 +0000 Richard Knox 12821 at http://ktep.org More Patients Keep HIV At Bay Without Antiviral Drugs Cardiac Arrest Survivors Have Better Outlook Than Doctors Think http://ktep.org/post/cardiac-arrest-survivors-have-better-outlook-doctors-think Every day something like 550 hospitalized Americans suffer <a href="http://www.nlm.nih.gov/medlineplus/cardiacarrest.html">cardiac arrest</a>. That's bad news. Only about one in five will live to leave the hospital.<p>But for the lucky 44,000 a year who are resuscitated and survive, the outlook is much better than expected, authors of a <a href="http://www.nejm.org/doi/full/10.1056/NEJMoa1200657">new study</a> say.<p>A year later, 60 percent of these survivors will still be alive, the study finds – substantially more than most doctors probably think. Thu, 14 Mar 2013 16:04:00 +0000 Richard Knox 12725 at http://ktep.org Cardiac Arrest Survivors Have Better Outlook Than Doctors Think Why Relatives Should Be Allowed To Watch CPR On Loved Ones http://ktep.org/post/why-relatives-should-be-allowed-watch-cpr-loved-ones Picture this: Your spouse or child has collapsed and isn't breathing. You call 911, and the paramedics rush in and take charge. But you are banished to another room while the medical people try to bring your loved one back to life.<p>It's about the most stressful scene imaginable. And it's what usually happens.<p>But now comes the most rigorous <a href="http://www.nejm.org/doi/full/10.1056/NEJMoa1203366">study</a> so far on allowing family members to witness CPR — its impact on them, on the medical team, on the CPR itself. Wed, 13 Mar 2013 22:24:00 +0000 Richard Knox 12678 at http://ktep.org Why Relatives Should Be Allowed To Watch CPR On Loved Ones Aspirin Vs. Melanoma: Study Suggests Headache Pill Prevents Deadly Skin Cancer http://ktep.org/post/aspirin-vs-melanoma-study-suggests-headache-pill-prevents-deadly-skin-cancer It's not the first study that finds the lowly aspirin may protect against the deadliest kind of skin cancer, but it is one of the largest.<p>And it adds to a <a href="http://www.cancer.gov/ncicancerbulletin/012511/page5">mounting pile of studies</a> suggesting that cheap, common aspirin lowers the risk of many cancers — of the colon, breast, esophagus, stomach, prostate, bladder and ovary.<p>The new study, in the journal <em>Cancer</em>, looked at melanoma in 60,000 post-menopausal Caucasian women. Mon, 11 Mar 2013 09:10:00 +0000 Richard Knox 12465 at http://ktep.org Aspirin Vs. Melanoma: Study Suggests Headache Pill Prevents Deadly Skin Cancer Mississippi Toddler Could Be First Child Cured Of HIV http://ktep.org/post/mississippi-toddler-could-be-first-child-cured-hiv A child born with HIV has been cured of the virus, researchers say. Audie Cornish talks to Richard Knox about what was different about this child among the millions who've been treated in the past and what it means for the prospect of an HIV cure in adults. Mon, 04 Mar 2013 21:43:00 +0000 Richard Knox 12043 at http://ktep.org Scientists Report First Cure of HIV In A Child, Say It's A Game-Changer http://ktep.org/post/scientists-report-first-cure-hiv-child-say-its-game-changer Scientists believe a little girl born with HIV has been cured of the infection.<p>She's the first child and only the second person in the world known to have been cured since the virus touched off a global pandemic nearly 32 years ago.<p>Doctors aren't releasing the child's name, but we know she was born in Mississippi and is now 2 1/2 years old — and healthy. Scientists presented details of the case Sunday at a <a href="http://www.retroconference.org/">scientific conference</a> in Atlanta.<p>The case has big implications. Sun, 03 Mar 2013 21:41:00 +0000 Richard Knox 11978 at http://ktep.org Scientists Report First Cure of HIV In A Child, Say It's A Game-Changer Younger Women Have Rising Rate Of Advanced Breast Cancer, Study Says http://ktep.org/post/younger-women-have-rising-rate-advanced-breast-cancer-study-says Researchers <a href="http://media.jamanetwork.com/news-item/study-finds-small-increase-in-incidence-of-advanced-breast-cancer-among-younger-women/">say</a> more young American women are being diagnosed with advanced breast cancer.<p>It's a newly recognized trend. The numbers are small, but it's been going on for a generation. And the trend has accelerated in recent years.<p>The discovery had unusual origins in a Houston book group about seven years ago. Three of the women in the group were diagnosed with breast cancer. Wed, 27 Feb 2013 08:35:00 +0000 Richard Knox 11660 at http://ktep.org Younger Women Have Rising Rate Of Advanced Breast Cancer, Study Says Medical Waste: 90 More Don'ts For Your Doctor http://ktep.org/post/medical-waste-90-more-donts-your-doctor Doctors do stuff — tests, procedures, drug regimens and operations. It's what they're trained to do, what they're paid to do and often what they fear not doing.<p>So it's pretty significant that a <a href="http://www.abimfoundation.org/Initiatives/Choosing-Wisely.aspx">broad array of medical specialty groups</a> is issuing an expanding list of don'ts for physicians.<p>Don't induce labor or perform a cesarean section for a baby who's less than full term unless there's a valid medical reason, say the American College of Obstetrics and Gynecology and the American Academy of Family Physicians. Thu, 21 Feb 2013 14:23:00 +0000 Richard Knox 11305 at http://ktep.org Medical Waste: 90 More Don'ts For Your Doctor Targeted Cancer Drugs Keep Myeloma Patients Up And Running http://ktep.org/post/targeted-cancer-drugs-keep-myeloma-patients-and-running Don Wright got diagnosed with multiple myeloma at what turned out to be the right time. It was 10 years ago, when he was 62.<p>That was at the beginning of a revolution in treating this once-fearsome <a href="http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001609/">blood cell cancer</a>, which strikes around <a href="http://practicingclinicians.com/myeloma/Multiple%20Myeloma%20-%20The%20Basics.pdf">20,000 Americans</a> every year. Mon, 18 Feb 2013 08:34:00 +0000 Richard Knox 11091 at http://ktep.org Targeted Cancer Drugs Keep Myeloma Patients Up And Running World's Most Popular Painkiller Raises Heart Attack Risk http://ktep.org/post/worlds-most-popular-painkiller-raises-heart-attack-risk The painkiller diclofenac isn't very popular in the U.S., but it's by far the most widely used non-steroidal anti-inflammatory drug, or NSAID, in the world.<p>A slew of studies, though, show <a href="http://www.rxlist.com/voltaren-drug.htm">diclofenac</a> — sold under the brand names Voltaren, Cambia, Cataflam and Zipsor — is just as likely to cause a heart attack as the discredited painkiller Vioxx (rofecoxib), which was <a href="http://www.npr.org/templates/story/story.php?storyId=4054991">pulled from the U.S. Tue, 12 Feb 2013 23:13:00 +0000 Richard Knox 10766 at http://ktep.org World's Most Popular Painkiller Raises Heart Attack Risk Experimental Tuberculosis Vaccine Fails To Protect Infants http://ktep.org/post/experimental-tuberculosis-vaccine-fails-protect-infants Researchers are disappointed in the results of a long-awaited study of the leading candidate vaccine against <a href="http://www.nlm.nih.gov/medlineplus/tuberculosis.html">tuberculosis</a>, one of humankind's most elusive scourges.<p>But, pointing to more than a dozen other TB vaccines in the pipeline, they say they're not discouraged.<p>The results show that an experimental vaccine known as <a href="http://www.aeras.org/portfolio/background.php?id=20">MVA85A</a> didn't provide much protection for South African infants against either infection with TB or development of the disease.<p>Earlier, Mon, 04 Feb 2013 15:37:00 +0000 Richard Knox 10154 at http://ktep.org Experimental Tuberculosis Vaccine Fails To Protect Infants Female Smokers Face Greater Risk Than Previously Thought http://ktep.org/post/female-smokers-face-greater-risk-previously-thought There's still more to learn about the risks of smoking and the benefits of quitting.<p>Studies in this week's <em>New England Journal of Medicine</em> show that the risk for women has been under-appreciated for decades. New data also quantify the surprising payoffs of smoking cessation — especially under the age of 40.<p>Dr. Prabhat Jha of St. Michael's Hospital in Toronto, an author of <a href="http://www.nejm.org/doi/full/10.1056/NEJMsa1211128">one study</a>, says before now it hasn't been possible to gauge female smokers' true risks. Thu, 24 Jan 2013 08:40:00 +0000 Richard Knox 9438 at http://ktep.org Female Smokers Face Greater Risk Than Previously Thought Old Drug Extends Life For Pancreatic Cancer Patients http://ktep.org/post/old-drug-extends-life-pancreatic-cancer-patients A large <a href="http://www.tgen.org/news/index.cfm?newsid=2111">study</a> is providing a rare glimmer of hope for patients with <a href="http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001283/">pancreatic cancer</a>, perhaps the deadliest of all malignancies.<p>By the time they're diagnosed, most patients with pancreatic cancer have advanced disease that's spread to the liver and lung. And the primary tumor may be inoperable because it's wrapped around vital blood vessels and nerves.<p>A two-drug combination extends life for such patients compared to standard chemotherapy. Wed, 23 Jan 2013 16:55:00 +0000 Richard Knox 9404 at http://ktep.org Old Drug Extends Life For Pancreatic Cancer Patients